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2025, 12, v.12 1427-1430
手术时机对创伤性脑出血患者预后的影响
基金项目(Foundation):
邮箱(Email): GuochangkfjZZ91@163.com;
DOI: 10.13919/j.issn.2095-6274.ZHJY202505009
摘要:

目的 探讨分析手术时机对创伤性脑出血患者预后的影响。方法 纳入漳州第三医院神经外科2019年9月至2024年12月收治的104例创伤性脑出血患者,以随机数字表法分为对照组、观察组,每组52例,对照组实施初始保守治疗,观察组采用早期手术治疗;对两组患者预后情况、昏迷与神经缺损评分、并发症发生率、死亡率比较分析。结果 观察组预后表现为Ⅳ级、Ⅴ级的患者数量高于对照组,差异有统计学意义(P<0.05)。干预前昏迷与神经缺损评分未见差异(P > 0.05),干预后观察组GCS高于对照组,观察组NIHSS低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率、死亡率均低于对照组,差异有统计学意义(P<0.05)。结论 对于创伤性脑出血患者,为其提供不同手术治疗时机,其中接受早期手术治疗的患者其预后效果更理想,患者神经功能得到更显著改善,降低并发症与死亡概率。

Abstract:

Objective To investigate the impact of surgical timing on the prognosis of patients with traumatic intracranial hemorrhage. Methods A total of 104 patients with traumatic intracranial hemorrhage admitted to the Department of Neurosurgery at Zhangzhou Third Hospital from September 2019 to December 2024 were enrolled and randomized by a random number table into a control group and an early-surgery group(n=52 each). The control group received initial conservative management, while the early-surgery group underwent early surgical intervention. Functional outcomes, levels of consciousness and neurological deficit scores, complication rates, and mortality were compared between groups. Results The number of patients achieving outcome grades IV–V was higher in the early-surgery group than in the control group(P<0.05). There were no between-group differences in Glasgow Coma Scale(GCS) and National Institutes of Health Stroke Scale(NIHSS) scores before intervention(P>0.05). Post-intervention, GCS was higher and NIHSS was lower in the early-surgery group compared with the control group(both P<0.05). The incidence of complications and the mortality rate were both lower in the early-surgery group than in the control group(both P<0.05). Conclusion Among patients with traumatic intracranial hemorrhage, earlier surgical intervention is associated with more favorable clinical outcomes, greater improvement in neurological function, and reduced risks of complications and death.

参考文献

[1]李炎明,嵇金陵,文柯,等.创伤性脑出血患者血清25(OH)D、IL-4水平与脑水肿体积、疾病转归的关系[J].分子诊断与治疗杂志,2025,17(3):512-515.

[2]黄海生,李东朋,陈轩.立体定向辅助微创血肿引流与CT引导下血肿穿刺术治疗中等量创伤性脑出血的安全性及近期效果比较研究[J].河南外科学杂志, 2024,30(3):86-88.

[3]王小菊,曾茂生,徐小青,等.冬病夏治穴位注射联合情志护理在创伤性脑出血患者中的应用效果评价[J].基层医学论坛,2024,28(35):153-156.

[4]中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国脑出血诊治指南(2019)[J].中华神经科杂志,2019,52(12):994-1005.

[5]格拉斯哥预后量表(GOS)简介[J].临床荟萃, 2010,(13):1122.

[6]周卫红,许民辉,周继红.颅脑创伤严重程度与结局评分的方法--格拉斯哥评分[J].伤害医学(电子版), 2013(3):31-36.

[7]陶子荣.我国脑卒中患者临床神经功能缺损评分标准信度、效度及敏感度的评价[J].第二军医大学学报, 2009,30(3):283-285.

[8]张晓敏.基于目标设置的分级护理在创伤性脑出血开颅术患者中的应用效果[J].中国社区医师, 2025,41(1):123-125.

[9]王久吉,郭红民,赵海洋,等.血清微RNA预测非创伤性脑出血早期神经功能恶化的价值分析[J].华西医学, 2023,38(5):704-709.

[10]曹娅妮,刘媛媛,杨丽辉.创伤性脑出血术后并发迟发性脑出血患者不良预后风险的Logistic回归模型构建[J].中国急救复苏与灾害医学杂志, 2023,18(7):880-883,896.

[11]赵世男,王小龙.不同手术时机治疗高血压性脑出血的研究现状及进展[J].临床医学进展, 2025,15(3):2521-2527.

[12]张要田,王军宝,马昌宝,等.创伤性脑出血患者脑水肿体积与血清NSE、MMP-9、NGAL的关系[J].实用心脑肺血管病杂志,2023,31(11):31-34.

[13]Wu Z, Chen D, Pan C, et al. Surgical robotics for intracerebral hemorrhage treatment:state of the art and future directions[J]. Ann Biomed Eng, 2023,51(9):1933-1941.

[14]Zhang G, Li Y, Chen D, et al. The role of ICP monitoring in minimally invasive surgery for the management of intracerebral hemorrhage[J].Transl Stroke Res, 2023,29:1-10.

[15]张要田,王军宝,马昌宝,等.创伤性脑出血患者脑水肿体积与血清NSE、MMP-9、NGAL的关系[J].实用心脑肺血管病杂志,2023,31(11):31-34.

[16]Jiao M, Li X, Liu H, et al. Aqueous Grown Quantum Dots with Robust Near-Infrared Fluorescence for Integrated Traumatic Brain Injury Diagnosis and Surgical Monitoring[J]. ACS nano, 2024,18(29):19038-19053.

[17]陆汝斌.标准化超早期微创伤性颅内血肿清除术治疗高龄脑出血患者的效果研究[J].中国标准化, 2024(24):299-302.

[18]王翠,杨畅,金玉,等.针刺调节RhoA/ROCK信号通路对创伤性脑出血大鼠血脑屏障的影响[J].中西医结合心脑血管病杂志,2023,21(15):2773-2776.

基本信息:

DOI:10.13919/j.issn.2095-6274.ZHJY202505009

中图分类号:R651.15

引用信息:

[1]李野鹏,郭长康.手术时机对创伤性脑出血患者预后的影响[J].中华灾害救援医学,2025,12(12):1427-1430.DOI:10.13919/j.issn.2095-6274.ZHJY202505009.

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